426 research outputs found
Scalar Asymptotic Charges and Dual Large Gauge Transformations
In recent years soft factorization theorems in scattering amplitudes have
been reinterpreted as conservation laws of asymptotic charges. In gauge,
gravity, and higher spin theories the asymptotic charges can be understood as
canonical generators of large gauge symmetries. Such a symmetry interpretation
has been so far missing for scalar soft theorems. We remedy this situation by
treating the massless scalar field in terms of a dual two-form gauge field. We
show that the asymptotic charges associated to the scalar soft theorem can be
understood as generators of large gauge transformations of the dual two-form
field.
The dual picture introduces two new puzzles: the charges have very unexpected
Poisson brackets with the fields, and the monopole term does not always have a
dual gauge transformation interpretation. We find analogs of these two
properties in the Kramers-Wannier duality on a finite lattice, indicating that
the free scalar theory has new edge modes at infinity that canonically commute
with all the bulk degrees of freedom.Comment: 16 pages, 2 figure
Dynamical Surface Gravity in Spherically Symmetric Black Hole Formation
We study dynamical surface gravity in a general spherically symmetric setting
using Painlev\'{e}-Gullstrand (PG) coordinates. Our analysis includes several
definitions that have been proposed in the past as well as two new definitions
adapted to PG coordinates. Various properties are considered, including general
covariance, value at extremality, locality and static limit. We illustrate with
specific examples of "dirty" black holes that even for spacetimes possessing a
global timelike Killing vector, local definitions of surface gravity can differ
substantially from "non-local" ones that require an asymptotic normalization
condition. Finally, we present numerical calculations of dynamical surface
gravity for black hole formation via spherically symmetric scalar field
collapse. Our results highlight the differences between the various definitions
in a dynamical setting and provide further insight into the distinction between
local and non-local definitions of surface gravity.Comment: Final version to appear in Phys. Rev. D. Slight name change, further
improvements to numerics and presentation, 25 pages, 7 figure
Vertex Expansion for the Bianchi I model
A perturbative expansion of Loop Quantum Cosmological transitions amplitudes
of Bianchi I models is performed. Following the procedure outlined in [1,2] for
isotropic models, it is shown that the resulting expansion can be written in
the form of a series of amplitudes each with a fixed number of transitions
mimicking a spin foam expansion. This analogy is more complete than in the
isotropic case, since there are now the additional anisotropic degrees of
freedom which play the role of `colouring' of the spin foams. Furthermore, the
isotropic expansion is recovered by integrating out the anisotropies.Comment: 15 pages, 2 figure
Color Fields on the Light-Shell
We study the classical color radiation from very high energy collisions that
produce colored particles. In the extreme high energy limit, the classical
color fields are confined to a light-shell expanding at and are associated
with a non-linear -model on the 2D light-shell with specific symmetry
breaking terms. We argue that the quantum version of this picture exhibits
asymptotic freedom and may be a useful starting point for an effective
light-shell theory of the structure between the jets at a very high energy
collider.Comment: 11 pages, no figure
Polymer quantization, singularity resolution and the 1/r^2 potential
We present a polymer quantization of the -lambda/r^2 potential on the
positive real line and compute numerically the bound state eigenenergies in
terms of the dimensionless coupling constant lambda. The singularity at the
origin is handled in two ways: first, by regularizing the potential and
adopting either symmetric or antisymmetric boundary conditions; second, by
keeping the potential unregularized but allowing the singularity to be balanced
by an antisymmetric boundary condition. The results are compared to the
semiclassical limit of the polymer theory and to the conventional Schrodinger
quantization on L_2(R_+). The various quantization schemes are in excellent
agreement for the highly excited states but differ for the low-lying states,
and the polymer spectrum is bounded below even when the Schrodinger spectrum is
not. We find as expected that for the antisymmetric boundary condition the
regularization of the potential is redundant: the polymer quantum theory is
well defined even with the unregularized potential and the regularization of
the potential does not significantly affect the spectrum.Comment: 21 pages, LaTeX including 7 figures. v2: analytic bounds improved;
references adde
Multiple-event probability in general-relativistic quantum mechanics: a discrete model
We introduce a simple quantum mechanical model in which time and space are
discrete and periodic. These features avoid the complications related to
continuous-spectrum operators and infinite-norm states. The model provides a
tool for discussing the probabilistic interpretation of generally-covariant
quantum systems, without the confusion generated by spurious infinities. We use
the model to illustrate the formalism of general-relativistic quantum
mechanics, and to test the definition of multiple-event probability introduced
in a companion paper. We consider a version of the model with unitary
time-evolution and a version without unitary time-evolutio
Revisiting the quantum scalar field in spherically symmetric quantum gravity
We extend previous results in spherically symmetric gravitational systems
coupled with a massless scalar field within the loop quantum gravity framework.
As starting point, we take the Schwarzschild spacetime. The results presented
here rely on the uniform discretization method. We are able to minimize the
associated discrete master constraint using a variational method. The trial
state for the vacuum consists of a direct product of a Fock vacuum for the
matter part and a Gaussian centered around the classical Schwarzschild
solution. This paper follows the line of research presented by Gambini, Pullin
and Rastgoo and a comparison between their result and the one given in this
work is made.Comment: 16 page
Novel anticancer drug 5h-pyro[3,2-a] phenoxazin-5-one (PPH) regulates lncRNA HOTAIR and HOXC genes in human MCF-7 cells
Breast cancer in women is the second most commonly cancer, after skin cancer. The percentage of mortality risk for breast cancer is 1 in 37 women (2.7%), which makes breast cancer represent the second cause of cancer death in women. Recently, new research based on previously published work in systemic chemotherapy and endocrine therapy field, have improved the incidence rates. The quinonic nucleus is common to many natural and synthetic products associated with anticancer and antibacterial activities, these compounds are typically DNA-intercalating agents. The Class I Homeobox genes (HOX in human and hox in mouse) control embryonic development and specific determination of positional identity anteroposterior axis of the human body. The HOX genes, are 39 transcription factors related to morphological, physiological disease. It has been demonstrated that any deregulation into the network is able to induce neoplastic transformation. Particularly, HOXC locus collaborating with lncRNA HOTAIR play a key role in breast cancer. In this study, our group evaluated the chemical and metabolic stability of new anticancer molecule 5H-pyro[3,2-a] phenoxazin-5-one (PPH). In a recent paper, we have already demonstrated that a new and potent anticancer synthetic iminoquinone, the 5H-pyrido[3,2-a]phenoxazin-5-one (PPH), is able to inhibit a large number of lymphoblastoid and solid-tumor-derived cells at submicromolar concentrations. Based on our previous research, we decided to analyze the cytotoxic effect and capability of PPH to control the lncRNA HOTAIR and HOXC locus gene expression in human breast cancer cells MCF-7, in order to demonstrate its role like potential new breast cancer antitumor drug
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